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We combine modern AI variant interpretation with whole-genome sequencing to build the most comprehensive genomic-insights platform we can. Today you can preview the full pipeline on a public reference genome while we complete the controls for public launch.
Unlike typical DNA tests that read less than 1% of the genome, Humanome is built around whole genome sequencing (WGS) and whole exome sequencing (WES) — 100% of the coding genome. During this alpha we demonstrate the full pipeline end-to-end on the public GIAB NA12878 reference genome (not a customer sample, not clinical output).
Our variant-classification engine applies ACMG/AMP guidelines and correlates findings against ClinVar and gnomAD. You can see exactly how it works today on the NA12878 reference genome; when public ordering opens, the same pipeline will run on your own sequencing results.
Genomic science evolves, so the interpretation should too. The Sentinel monitoring system is designed to re-scan a genome as new ClinVar/gnomAD releases land and surface reclassifications. We run this against the reference genome today; per-customer monitoring follows public launch.
Humanome is a founder-only, non-regulated alpha: data is encrypted at rest, access is restricted to the owner allow-list, and public ordering is disabled. No HIPAA/PHI or non-founder workflow is live.
The planned consumer flow is a single sample collection at a partner lab (Quest Diagnostics integration is in development), feeding the same sequencing-and-interpretation pipeline you can preview today on the reference genome. Public collection opens after FDA notification.
Our interpretation engine goes beyond simple database lookups, combining ACMG/AMP criteria with the ClinVar and gnomAD reference databases to classify variants. You can watch it run today on the public NA12878 reference genome — not clinical output, and not a diagnosis.
Real-time variant analysis
We are building on industry-standard tools and databases so every step of the sequencing-and-interpretation pipeline meets a high quality bar. Lab integrations are in development ahead of public launch.
Laboratory Partner
Industry-leading clinical laboratory with 2,200+ patient service centers nationwide for convenient sample collection.
Variant Calling
State-of-the-art deep learning technology for highly accurate variant identification from sequencing data.
Reference Databases
Authoritative genomic databases providing clinical significance and population frequency data for variant interpretation.
Infrastructure
Encrypted cloud infrastructure restricted to the founder-only alpha; it is not represented as a live regulated clinical service.
Genetic information is among the most sensitive data a person owns, so the platform is built around encryption at rest and in transit plus strict access controls. The current deployment is limited to owner/founder data and is not a HIPAA/PHI workflow. A signed BAA and full regulated controls are prerequisites before any non-founder health data.
Owner allow-list; no non-founder regulated health-data workflow
AES-256 encryption at rest and in transit
Download or delete your data at any time